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ETHYL OLEATE FOR SYNTHESIS 98%
Product Qty Per Unit:
0.00
Product usage unit:
Box
Product Delivery Locations:
Visakhapatnam, Vijayawada, Kakinada, Gangavaram, Krishnapatnam, Rawa, Nellore, Rajahmundry
ETHYL OLEATE FOR SYNTHESIS 98%
Product Description:
Ethyl oleate uses Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids. It also finds use as a lubricant and a plasticizer.
Product Application:
- E 1625 (OTTO) Ethyl oleate, 99% Cas 111-62-6 - used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac).
Product Procedure:
Product Note:
- The ethyl oleate used by the submitters was prepared by esterification of commercial U.S.P. grade oleic acid and fractionated through a Widmer column. The fraction boiling at 160–170°/1 mm., nD25 1.4482–1.4570, iodine value 83.6 (calculated 81.8), was used.
- The purity of the absolute ethanol is of prime importance. Ethanol dried only by a lime process gives a low yield (20–25%). The ethanol used in this procedure was dried over lime and then over aluminum tert-butoxide, after which it was distilled directly into the flask used for the reaction.
- The submitters used a modified Widmer column; the checkers, a Claisen flask modified with a short Vigreux column.
Product Technical Specification:
Product pack size:
Product alias:
<p>
ETHYL OLEATE FOR SYNTHESIS 98%</p>
Remarks:
SKU:
RXSOL-60-6604-568
Title:
ETHYL OLEATE FOR SYNTHESIS 98%