Anthranilic acid supplier in vizag visakhapatnam india

Anthranilic acid (o-amino-benzoic acid, 2-aminobenzoic acid, 2-AA, 2AA, AA) is an aromatic acid with the formula C6H4(NH2)(CO2H). The molecule consists of a substituted benzene ring, hence is classed as aromatic, with two adjacent, or "ortho-" functional groups, a carboxylic acid and an amine. The compound is consequently amphoteric. In appearance, anthranilic acid is a white solid when pure, although commercial samples may appear yellow. It is sometimes referred to as vitamin L1 and has a sweetish taste. The anion [C6H4(NH2)(CO2)]−, obtained by the deprotonation of anthranilic acid, is called anthranilate.

Industrially, anthranilic acid is an intermediate in the production of azo dyes and saccharin. It and its esters are used in preparing perfumes to imitate jasmine and orange, pharmaceuticals (loop diuretics e.g. furosemide) and UV-absorber as well as corrosion inhibitors for metals and mold inhibitors in soy sauce.

Anthranilic acid can be used in organic synthesis to generate benzyne. The benzyne rapidly dimerizes to form biphenylene. It reacts with phosgene to give isatoic anhydride, a versatile reagent.

Chlorination of anthranilic acid gives the 2,4-dichloro derivative.

Anthranilate-based insect repellents have been proposed as replacements for DEET.

Fenamic acid is a derivative of anthranilic acid,:235 which in turn is a nitrogen isostere of salicylic acid, which is the active metabolite of aspirin.:235 Several non-steroidal anti-inflammatory drugs, including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid are derived from fenamic acid or anthranilic acid and are called "anthranilic acid derivatives" or "fenamates.

Production

Many routes to anthranilic acid have been described. Industrially it is produced from phthalic anhydride, beginning with amination:The resulting sodium salt of phthalamic acid is decarbonylated via a Hofmann rearrangement of the amide group, induced by hypochlorite:A related method involves treating phthalimide with sodium hypobromite in aqueous sodium hydroxide, followed by neutralization.In the era when indigo dye was obtained from plants, it was degraded to give anthranilic acid.Anthranilic acid was first obtained by base-induced degradation of indigo.