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Xylene, xylol or dimethylbenzene is any one of three isomers of dimethylbenzene, or a combination thereof. With the formula (CH3)2C6H4, each of the three compounds has a central benzene ring with two methyl groups attached at substituents. They are all colorless, flammable liquids, some of which are of great industrial value. The mixture is referred to as both xylene and, more precisely, xylenes.

Applications
Terephthalic acid and related derivatives
p-Xylene is the principal precursor to terephthalic acid and dimethyl terephthalate, both monomers used in the production of polyethylene terephthalate (PET) plastic bottles and polyester clothing. 98% of p-xylene production, and half of all xylenes produced is consumed in this manner. o-Xylene is an important precursor to phthalic anhydride. The demand for isophthalic acid is relatively modest so m-xylene is rarely sought (and hence the utility of its conversion to the o- and p-isomers).

Solvent applications and industrial purposes
Xylene is used as a solvent. In this application, with a mixture of isomers, it is often referred to as xylenes or xylol. Solvent xylene often contains a small percentage of ethylbenzene. Like the individual isomers, the mixture is colorless, sweet-smelling, and highly flammable. Areas of application include the printing, rubber, and leather industries. It is a common component of ink, rubber, and adhesives. In thinning paints and varnishes, it can be substituted for toluene where slower drying is desired, and thus is used by conservators of art objects in solubility testing. Similarly it is a cleaning agent, e.g., for steel, silicon wafers, and integrated circuits. In dentistry, xylene can be used to dissolve gutta percha, a material used for endodontics (root canal treatments). In the petroleum industry, xylene is also a frequent component of paraffin solvents, used when the tubing becomes clogged with paraffin wax. For similar reasons, it is often the active ingredient in commercial products for ear wax (cerumen) removal.

Laboratory use
Xylene is used in the laboratory to make baths with dry ice to cool reaction vessels, and as a solvent to remove synthetic immersion oil from the microscope objective in light microscopy. In histology, xylene is the most widely used clearing agent. Xylene is used to remove paraffin from dried microscope slides prior to staining. After staining, microscope slides are put in xylene prior to mounting with a coverslip.