Sodium thiosulfate supplier manufacture in andhrapradesh India

Sodium thiosulfate (sodium thiosulphate) is a chemical and medication. As a medication, it is used to treat cyanide poisoning and pityriasis versicolor.It is an inorganic compound with the formula Na2S2O3.xH2O. Typically it is available as the white or colorless pentahydrate, Na2S2O3·5H2O. The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water. It is also called sodium hyposulfite or “hypo”.It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.
Uses
Medical uses
It is used as an antidote to cyanide poisoning. Thiosulfate serves as a sulfur donor for the conversion of cyanide to thiocyanate (which can then be safely excreted in the urine), catalyzed by the enzyme rhodanese. For this purpose, it is used together with sodium nitrite.
It has been used as a treatment of calciphylaxis in hemodialysis people with end-stage kidney disease.There is apparently an incompletely understood phenomenon whereby this causes severe metabolic acidosis in some patients.
In foot baths for prophylaxis of ringworm, and as a topical antifungal agent for tinea versicolor.It is used in the management of extravasations during chemotherapy. Sodium thiosulfate prevents alkylation and tissue destruction by providing a substrate for the alkylating agents that have invaded the subcutaneous tissues. The dose may be 2 ml of 0.17 M (a solution of 4 ml 10% sodium thiosulfate and 6 ml sterile water for injection). It may be instilled subcutaneously into multiple sites using a small-gauge needle. Data are limited on this method with few recommendations.[citation needed]
In measuring the volume of extracellular body fluid and the renal glomerular filtration rate.Sodium Thiosulfate can be used to neutralize and ameliorate renal toxicity of the chemotherapeutic agent Cisplatin.
 

Sodium thiosulfate is also used:

As a component in hand warmers and other chemical heating pads that produce heat by exothermic crystallization of a supercooled solution.In bacteriological water assessment, as it promotes the survival of coliform organisms by neutralizing residual chlorine.In the tanning of leather demonstrate the concept of supercooling in physics classes: Sodium thiosulfate, when heated, dissolves in its own water of crystallization. This solution can be cooled to room temperature without recrystallization. 

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